Structural Brain Network Disturbances in the Psychosis Spectrum

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Structural Brain Network Disturbances in the Psychosis Spectrum.

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BACKGROUND Investigation of aberrant large-scale brain networks offers novel insight into the role these networks play in diverse psychiatric disorders such as schizophrenia. Although studies report altered functional brain connectivity in participants at ultra-high risk (UHR) for psychosis, it is unclear whether these alterations extend to structural brain networks. METHODS Whole-brain struc...

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OBJECTIVE Structural magnetic resonance imaging (MRI) studies that focus on first-episode psychosis avoid some common confounds, such as chronicity of illness, treatment effects, and long-term substance abuse. However, such studies may select subjects with poor short-term treatment response or outcome. In this study, the authors focus on structural brain abnormalities in never or minimally trea...

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ژورنال

عنوان ژورنال: Schizophrenia Bulletin

سال: 2015

ISSN: 0586-7614,1745-1701

DOI: 10.1093/schbul/sbv178